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The size and shape of a polysaccharide can be ascertained by techniques that are usually applied to large molecules; e.g., the most accurate molecular weight determination measures the sedimentation properties of the molecule in an applied gravitational field (e.g., the rate at which a solid material is deposited from a state of suspension or solution in a liquid).
The standard ADA determination measures ADA activity and not the absolute amount of enzyme present.
Quantitative polymerase chain reaction (qPCR) assay for telomere length determination measures telomere (T) signals and single copy gene (S) signals, in comparison to a reference DNA, to yield relative T/S ratios that are proportional to average telomere length (Table 1).
The discrepancy between q-PCR and small RNA blot analysis could be attributed to the fact that the small RNA blot analysis (hybridization-based determination) measures the abundance of entire miRNA family (most conserved miRNAs are represented by multiple members with the same sequence or sequence that differ by 1 or 2 nucleotides) whereas q-PCR is measuring one member of that particular family.
Bearing in mind that R, the coefficient of determination, measures the percentage of the variation in the dependent variable that is explained by variation in the independent variable, taking the compliment (100 – R) we see that 82% of the variation in the outcome parameter assessed is unexplained by the model.
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A ρ2 of 0.36 translates into a standard linear regression-based coefficient of determination measure of approximately 0.7 [34].
For mean or median door to balloon times, we did subgroup analyses by type of off-hours determination, measured time of presentation, and region, as well as meta-regression using the mid-year of enrollment of the cohort to evaluate time trends in door to balloon times.
We analyzed 391 mother child pairs with available phthalate and creatinine determinations measured in two spot-urine samples collected in the first (mean ± SD, 13.4 ± 1.7 gestational weeks) and third (mean ± SD, 34.1 ± 1.4 weeks) pregnancy trimesters.
"Tonight we proved that what matters most in life is the measure of your ideas, the measure of your determination, the measure of your friends, not the measure of your wallet," Mr. Murphy told an exultant crowd here.
Model selection based upon model-fitting criteria, such as Akaike's information criterion, Bayesian information criterion or the coefficient of determination, are standard measures considered when choosing a regression model.
The GMFE measure has the advantage of being less affected by extreme outliers, by comparison with the coefficient of determination (which measures the quadratic error) [35].
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