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It had taken the same determination for her to stride out of the surf, walk across the sea wrack -- a ridge of seaweed cluttered with plastic debris and a few stranded Portuguese men-of-war -- and lay her eggs on the beach.
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The accuracy of well-based RPPA for determination of HER-2 positive or negative breast cancer tissue samples was evaluated using receiver-operating characteristic (ROC) curve.
Kolma's determination for his wife to complete her education grew stronger each day until in early 2008, a newly established Christian Integrated School run by the Baptist Church in Minj accepted her to enrol in grade six.
To determine whether this assay provides an accurate alternative for the determination of HER-2/ neu status, we focused primarily on tumors that were deemed indeterminate or borderline status by IHC.
Thirty-nine breastumorsreceivinging an IHC score of 2+ were evaluated by both FISH and LightCycler® technologies in order to determine whether quantitative real-time PCR provides an accurate alternative for the determination of HER-2/ neu status.
For these authors, decreases in time and costs were quoted as strong arguments in favour of using this same testing algorithm for the determination of HER-2/ neu status.
Nevertheless, the accuracy of this technique means that FISH assessment is accepted as the "gold standard" for the determination of HER-2/ neu status in paraffin embedded breast tumors.
These results therefore suggest that real-time PCR analysis, using the LightCycler®, is a viable alternative to FISH for reassessing breast tumors which receive an IHC score of 2+, and that a combined IHC and real-time PCR approach for the determination of HER-2 status in breast cancer patients may be an effective and efficient strategy.
Expression of phosphorylated Her-2/ neu was visually assessed using the same scoring system applied for determination of Her-2/ neu overexpression (see above).
Dorothy Hodgkin (1910-1994) - British chemist, awarded the Nobel prize for chemistry in 1964 for "her determinations by X-ray techniques of the structures of important biochemical substances".
We will sorely miss her determination, her caring concern for others and her good cheer.
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