Sentence examples for determination challenging from inspiring English sources

While the sensor performed reliably in acetate buffer with a LOD of 6 μM for Zn, detection in serum exhibited large variability, making determination challenging.

The high amount of missing values is due to the difficult assessment of this variable, because ongoing vaginal bleeding due to HRT and hysterectomy early in life without bilateral oophorectomy while still being premenopausal, make an age determination challenging and some women simply don't remember their age at menopause.

Every ethical dilemma, every test of integrity and every trial of determination challenges the character of all leaders, including emerging sales leaders.

For better or worse: not all these women are right, or lucky, or well­-intentioned, but at least they are shown as having power and self-determination, challenging the old literary cliche of a high-pitched simpering: "Oh but Lord Inserthisme-here, this isosuddenden!" But there must be many more examples of women's proposals and indirect proposals in books – add your favourite ones in the comments.

Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-electron microscopy approaches.

However, RNA often interacts with cofactors, which remain largely undefined or otherwise make structure determination more challenging.

HSQC chemical shift titration experiments with PK9119 and L. major SAS-697 274 SAS-697 274suggestllimolar binding affinity; the low solubility of PK9119 in aqueous solutions and lack of a reference comillimolar competition binding affinityakes more accuratheKD determinations technicalow challenging.

"What would make it change?" Mr. Podesta asked, referring to the Republican determination to challenge Mr. Obama.

Her determination to challenge Ms. Gillibrand has left her isolated in ways that few can understand.

The phrase summed up his determination to challenge conventions in overseas aid.

Instead it must surely mean a renewed determination to challenge unaccountable power and dehumanisation.