Definitions of adverse events and drug relationships, and the determination of seriousness basically complied with the "Definitions and Terminology Associated with Clinical Safety Experience" in the International Conference on Harmonisation (ICH -E2 [ 9].
Ensemble pruning is basically the determination and selection of the final base models that will form part of the ensemble model.
In this case, that's the ability to look at an image and make some sort of determination about its contents – basically, it's teaching machines to make the sort of intuitive leaps that people naturally do.
There are two important concepts that can help us make this determination: (a) weapon damage coefficient — basically, the extent of damage that the use of a particular weapon is designed to cause; and (b) minimum force necessary to produce a result — that result being protection against bodily harm.
Seven steps are basically employed: (i) determination of design objective, (ii) characteristics of site, rock mass and project, and identification of constraint conditions, (iii) selection or development of global design strategy, (iv) determination of modeling method and software, (v) preliminary design, (vi) comprehensive integrated method and dynamic feedback analysis, and (vii) final design.
"If you go around talking with people and nobody gets excited about your idea, then you should really think about whether it's a really exciting idea," Pond says half-jokingly. "Opening your own company is basically perseverance and determination, and you need a whole lot to make it a success".
The decisions consist basically of the determination of proper loading station's locations, the optimal type and number of transloaders in each loading station, and sugarcane field allocation to guarantee a continuous and uniform feeding of sugarcane to the sugar mill.
If the matter is life or death and no approved drug is available, McChesney said, "there's a point in there where the veterinarian gets involved and basically makes a risk determination".
Antimicrobial activity was estimated by minimum inhibitory concentration (MIC) determinations using a broth microdilution procedure basically according to a guideline of the Clinical Laboratory Standards Institute (14).
"The board of medical examiners is getting involved in what is basically a benefit or coverage determination," he said.
