Sentence examples for determination and maintenance from inspiring English sources

Finally, recent studies have revealed that the replication-coupled nucleosome assembly is important for the determination and maintenance of cell fate in multicellular organisms.

First, it inhibits chondrocyte cell lineage determination and maintenance [28].

Therefore, it is hypothesised that the extent of gene expression plasticity may contribute to the differentiation potency determination and maintenance of stem cells [14], [44].

We believe that the present data show that osteocytes are more metabolically active than hitherto understood and play a central role in the determination and maintenance of bone structure [24] [26].

The notion that the determination and maintenance of embryonic stem (ES) cell pluripotency and self-renewal is related to an epigenetic state characterized by an open chromatin conformation has received considerable support over the last several years [1] [6].

We detected the presence of the transcription factors Cdx2 and Eomes, which are critical for the determination and maintenance of the murine trophectoderm lineage [47], [48], in the derived vole cell lines.

Studies in mouse have identified Nr5a1 as a key gene involved in gonadal sex determination, differentiation, and maintenance.

Thus, sacy-1 links the somatic control of meiotic maturation to germline sex determination and the maintenance of oocyte quality.

SACY-1 is a multifunctional protein that establishes a mechanistic link connecting the somatic control of meiotic maturation to germline sex determination and gamete maintenance.

Importantly, Runx factors have been also widely shown to play particularly key roles in cell fate determination and the maintenance of stem cell populations [ 13- 15].

Among these pathways, sacy-1 acts as a strong negative regulator of meiotic maturation and provides a mechanistic connection to the fundamental germline processes of sex determination and gamete maintenance.