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These studies shed further light on the complex determinants within the viral CA gene product which control the susceptibility of murine and human cells to retroviral infection.
Here, we present an energetic analysis of the specificity determinants within the Bcl-2 family of proteins (key regulators of the intrinsic apoptotic pathway) via a total of ∼20 μs of simulation of 60 distinct protein-protein complexes.
The data are entirely consistent with actin being responsible for positioning of polymerization determinants within the SDV on the mesoscale.
In this case, rather than specifically positioning polymerization determinants within the SDV, actin could be shaping the silicalemma to provide a defined shape within which silica is precipitated.
This study aimed to identify serotype-independent virulence determinants within the genomes of a selection of serotype 1 isolates with wide-ranging virulence in both mice and humans.
Detailed studies of the dissemination of virulence and drug-resistance determinants within the carriage population may inform on containment and intervention strategies for community infection.
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Discerning the specificity determinants within these systems has proven a challenging task.
Attitude is an indirect determinant within the UTAUT model.
We used a high throughput ELISPOT approach to test for responses to every possible 9-mer determinant within the 191 residue hepatitis C core protein in addition to 61 previously defined CD8 cell determinants.
It is interesting to note that the third polymorphic determinant within the Thai isolate vacA sequence, the " i" region, shows marked differences to strain 95-54, whereas it shares greater homology to the other model strains.
Future studies aimed at understanding the determinants within RBRs that specify the type of product generated are needed to further our understanding of RBR mechanism and function.
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