The number of resistance determinants varies with four on pYR1, ten on pIP1202 and 13 on pSN254, several of which are present in multiple copies (Table 1 and Fig. 1).
As expected the L1 and L2, which are responsible for the neutralization ε determinant, clustered with HAdV-D22.
As AB picks up resistance determinants with great ease, one speculation could be that different antibiotic resistant mechanisms, which may be up-regulated or acquired, to a different extent during different antibiotics exposure, could possibly be found in related isolates.
In the third step we kept the two determinants with the lowest p-values (if both ≤ 0.15) and tentatively included the remaining determinants, one at a time.
Most of the genomic determinants associated with methylotrophy are nearly identical, with two exceptions that illustrate the metabolic and genomic versatility of Methylobacterium.
In agreement with this, the determinants for two other important enzymes of these pathways, 2-deoxy-D-gluconate 3-dehydrogenase (Bpet0046, Bpet1132) and altronate hydrolase (Bpet0414) are present, indicating that B. petrii uses plant cell-wall constituents as nutrient sources, which is in line with the isolation of a B. petrii strain from a plant root consortium [ 14].
Likewise, although income and occupation were not described as determinants, these two variables are related with socioeconomic status and will depend on education as well.
Detailed analysis of the molecular determinants of the Cav3.2/calnexin interaction revealed that Cav3.2 interacts with two distinct calnexin regions.
The perception of 'good' care is therefore a significant determinant of maternal satisfaction, with four sub-themes emerging as major determinants – length of consultation, completeness of procedures, perception of negligent care (which diminishes satisfaction) and perceived provider competence.
Combining the performance objectives with the selected determinants resulted in two matrices with change objectives for healthcare providers and patients, which interventions need to target.
