In our framework (see Figure 1) we have expanded Boerma and Weir (2005)'s proximate determinants framework to make explicit the country/regional, household and individual level, underlying determinants of HIV.
Study-based global health interventions, especially those that are conducted on an international or multi-site basis, frequently require site-specific adaptations in order to (1) respond to socio-cultural differences in risk determinants, (2) to make interventions more relevant to target population needs, and (3) in recognition of 'global health diplomacy' issues.
But Roger's studies do not give the information on (i) how these dimensions can be achieved; (ii) what are the determinants that help in making these dimensions; and (iii) what is the relative significance of these dimensions and determinant.
COs specify what changes in the determinants are needed to make the attainment of the POs most likely.
However, the sensitivity of these low stability determinants to domination makes the development of improved vectors that incorporate minimal antigenic baggage, and that do not entail complex administration schedules 41, critical.
With neoadjuvant chemotherapy, the primary breast cancer provides a unique opportunity for assessing predictive markers and for studying hypothesis-generating relationships, in that it allows for measurements of possible biologic determinants to be made before treatment in an intact human tumour.
The objective is to clarify the determinants involved in deciding to make said investment in a developing country.
(1) Religion is one of the determinants that leads corporations to make donations.
These new determinants include our ability to make the actual etiological diagnosis rather than treating empirically [40, 48, 50, 51, 85], delayed ICU admission [11], cytogenetic data in patients with aggressive malignancies [86], and, clearly, the number and the extent of organ dysfunctions [17, 26].
However, as there was a wide distribution of 25OHD3 and other determinants, it was possible to make internal comparisons between subjects.
