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Herein, we characterized the molecular determinants that underlie the pharmacological and cell-penetrating properties of maurocalcine.
Distribution of evolutionary conserved residues were compared to search for the structure determinants that underlie their diverse catalytic efficiency and those that may account for putative physiological substrate targets or other non-catalytic biological activities that contribute to the antipathogen role of the RNases involved in the host defence system.
Understanding the nature of the biological determinants that underlie severe illness has been a longstanding goal of V. cholerae research.
The last few years have witnessed an unprecedented interest and effort in identifying the genetic determinants that underlie susceptibility to human diseases.
have tried to define the set of genetic determinants that underlie this disparity.
Insight into the changes in physiological determinants that underlie the aerobic training - VO2peak relationship will further refine exercise guidelines and inform novel combination approaches to maximize health and longevity in this population, as well as elucidating the mechanisms of benefit.
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The aim of this study was to analyze the genome of JEV for any indication of strain virulence determinants that might underlie the difference in outcome of infection in pigs on the one hand, and man on the other.
In order to do this, it is imperative that we understand the social-cognitive determinants (including habits) that underlie healthcare professionals' intention and the corresponding behavior of actually encouraging patients with cardiovascular risk factors to engage in physical activity.
In this paper, we have argued for an increased attention to the wider financial incentive environment and a better understanding of the complex remuneration of health workers, its determinants and the factors that underlie it, as well as its wide-ranging consequences for behaviour and performance.
This marginalization may be one of the underlying determinants that governed their apparent lesser likelihood of obtaining an RDS coupon from any of the individuals in Arm 1.
As deep sequencing data expands, this global approach will undoubtedly uncover additional editing events and underlying determinants that will enhance our understanding of this post-transcriptional crosstalk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com