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Many of the most common cancers that blight our societies are very rare in other large populations in the world; studies of migrants exclude a simple genetic explanation for these wide geographical variations and imply that environmental exposures are key determinants of the development of these cancers.
The concentration of UCB in the brain and the duration of exposure to UCB are important determinants of the development of UCB neurotoxicity [49] [51].
Potential determinants of the development of acute and chronic WAD will be measured.
Sensitivity to oestrogens and apoptosis are critical determinants of the development and progression of breast cancer and reflect closely linked pathways in breast epithelial cells.
In addition, we assumed that a GP's experience and contextual knowledge would be important determinants of the development of gut feelings.
Dengue pathogenesis is not completely understood, and the main determinants of the development of severe forms are not yet well established.
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However, MTHFR or MS mutation were not strong determinants on the development of CAD.
A striking feature of these receptors and their downstream pathways is that they are important determinants of the growth, development and function of the normal breast epithelium [ 3, 4, 8, 9].
Volunteers also participated in a study of metabolic determinants for the development of type 2 diabetes and obesity.
Our results showed that a lower 30 min–to–15 min ratio was independently related to orthostatic hypotension in subjects with NGT, providing epidemiological evidence that a decreased cardiovagal response to standing was one of the determinants for the development of orthostatic hypotension.
The incidence of ESRD is 50% higher in males, which makes gender one of the most significant risk determinants for the development of kidney disease.
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