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Although the present study has a comparatively small sample size (n = 6042 patients including 2315 aged ≤ 40 years at diagnosis), the event rate is significantly higher over all patients (OS 18.2%, DFS 22.5%) and the early-onset subset (OS 26.1%, DFS 30.9%) which is one of the main determinants of power.
Studies of the determinants of power output (as a proxy for field strength) have given inconsistent results.
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So, let's look at a related determinant of power: culture.
A conceptual model of the hydrodynamics of the device has been formulated and shows that, as the motion of the flap is highly constrained, the magnitude of the wave force on the flap is the key determinant of power capture.
The social separation and status of physicians is a key determinant of power relations.
Another important determinant of power is the difference in effect size between treatment groups.
However, sample size in the replication stage is the most important determinant of power.
As "n" the number of animals per treatment is the main determinant of power of test [ 52], the authors considered it crucial that adequate group sizes of animals were used, however, optimal sample size is ultimately a function of the underlying parameters in the study.
Within the current CHORUS framework, the input parameter θ, which determines the number of combinations retained at each stage of the algorithm, can also be a determinant of power: if too few combinations are retained at the initial stages of the search, the risk of missing key higher-order interactions with intermediate levels of marginal effects is increased.
Chapman, J.M., Cooper, J.D., Todd, J.A. & Clayton, D.G. Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power.
Chapman, J. M., Cooper, J. D., Todd, J. A. & Clayton, D. G. Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com