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Third, environmental determinants may differ in different populations, partly depending on the genetic architecture.
This is because risk perception and its determinants may differ by actual risk.
The resulting variation in outcome measures may have contributed to the low number of consistent associations found in this review, as correlates and determinants may differ for various subcomponents of physical activity.
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However, it must be considered that this study was carried out with data from Catalonia, a region in the northeast of Spain, in 2006: the impact of intermediary determinants of inequalities may differ in different countries and welfare regimes (35), and at different points in time (for example, with changing economic contexts such as the current crisis affecting Southern Europe).
More subtle contextual factors can also play a role; for example, some methods might simply be more effective in some cultures than others, for example because determinant relevance may differ (McEachan, Conner, Taylor, & Lawton, 2011).
However, multiple lines of evidence suggest that the determinants of breast density may differ at different ages [ 26, 28, 29].
Our results also showed that the determinants of survival may differ between offspring stages.
In Type 2 diabetic, nephropathy, albuminuria may be more closely associated with decline in renal function and the impact of genetic determinants of eGFR may differ depending on the presence or absence of nephropathy; therefore, we examined the effects on eGFR stratified by albuminuria.
Further, there is evidence to suggest that walking and cycling, and their determinants, may also differ from each other.
Activities from different domains may differ in their determinants [ 5– 7] and knowledge about them could help to inform the development of effective physical activity interventions at a population level.
We expect that some determinants of healthy ageing may differ between Māori and non-Māori and this together with lower life expectancy means that to achieve sufficient explanatory power for Māori a specifically Māori cohort was needed separate from non-Māori.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com