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Just as the loss of segregating determinants leads to overgrowth and tumor formation, so too will the loss of machinery controlling mitotic spindle orientation.
Medication adherence promotion interventions may benefit from content targeting patients' medication adherence-related information, motivation, and behavioral skills and assessing the degree to which change in these determinants leads to changes in medication adherence behavior.
Although the machinery that segregates cell-fate determinants during mitosis is fairly well understood, it is currently unclear how the combined action of these determinants leads to differentiation (Doe, 2008; Knoblich, 2008; Reichert, 2011).
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Elucidating its magnitude, type and determinants lead to strategies to ease it.
A failure to account for important fertility and women's employment determinants leads thus to a selection bias to the estimated effect of women's employment on fertility.
Here, we describe a new translational pausing determinant that leads to SsrA peptide tagging of the E. coli GalE protein (UDP-galactose 4-epimerase).
Lack of the maternal determinant Nanos leads to severe abdomen defects.
Analysis of the determinants of stillbirth leads to the conclusion that over half are related to placental dysfunction and that many of these are associated with impaired fetal growth [ 2].
One such example is Abnormal Spindle-like, Microcephaly-associated (ASPM), which when mutated results in disruption of cleavage plane, and depletion of progenitor cells because of asymmetric localization of fate determinants that ultimately leads to a small brain (Knoblich, 2008).
Adopting the quantitative assessment of health and its determinants leads in turn to individual behavior choices and to a remedial strategy for a dysfunctional health care system.
Negative response to tests for amyloid has also been obtained for aggregates of the yeast prion determinant Sup35 which leads to non-fibrillar filaments [28].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com