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Inflammation and blood flow alterations are new markers emerging as possible determinants for the development of atherosclerotic lesions.
The purpose of this study is to examine the fetal and early childhood family-based determinants for the development of adiposity, CVD risk factors, and atherosclerosis in childhood.
The incidence of ESRD is 50% higher in males, which makes gender one of the most significant risk determinants for the development of kidney disease.
Volunteers also participated in a study of metabolic determinants for the development of type 2 diabetes and obesity.
Prior studies illustrated that the location of APOE mutations is an important determinants for the development of LPG.
Fiber length and persistence are thought to be determinants for the development of toxic, fibrogenic, and carcinogenic effects of fibrous dusts.
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In fact, studies with genetically engineered mice have revealed that the activity of lipoprotein lipase (LPL) is a major determinant for the development of obesity.
In working populations, AHR is an important determinant for the development of symptoms[ 3].
Chronically elevated BP is an important determinant for the development and progression of atherosclerosis, the underlying pathology for most cardiovascular events.
Thus, although neutrophil recruitment prevents the systemic spread of the infection, it might nevertheless be a key determinant for the development of gastroenteritis.
Recently, Ohno et al. showed that PPAR-γ ligands, coupled with PRDM16 (a determinant for the development of BAT), could switch subcutaneous white adipose cells to a BAT programme (Ohno et al., 2012).
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