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This dependence upon a combination of extrinsic and intrinsic determinants contributes to distinguish IFs from other fibrous cytoskeletal polymers and is key to their function.
Further, an important question is how the assessment of HrQoL and its determinants contributes to the understanding of children's needs and to the ability to provide improved care [ 20].
The aim of the present investigation was, therefore, to use the metal-specific snail MTs as model molecules and to test which of the above determinants contributes to the metal specificity in the snail MT system.
We identified two independent risk factors, i.e., Pro/Pro genotype and smoking, and we found that these two risk factors showed synergistic effects on the development of diabetic nephropathy in Chinese type 2 diabetic patients, supporting the idea that an interplay between genetic and nongenetic risk determinants contributes to the development and progression of diabetic nephropathy (14).
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In the current study, we investigate the molecular determinants contributing to receptor activation by endogenous ligands.
Biochemical and genetic studies have characterized molecular determinants contributing to alter Hcy metabolism.
This research analyzes how users' city attachment levels and other personal determinants contribute to their uses of urban services.
These plasmids function as virulence determinants, contributing to pathogenesis of S. enterica, especially during the systemic phase of the disease (Libby et al. 1997; Uzzau et al. 2000).
However, due to the absence of an experimental ATR structure, the determinants contributing to ATR inhibitors' potency and specificity are not well understood.
Asthma is a complex genetic disease with multiple genetic and environmental determinants contributing to the observed variability in response to common antiasthma therapies.
Due to the absence of an experimental CDK4 structure, the ligand and protein determinants contributing to CDK4 selectivity are poorly understood at present.
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