One of the most efficient and useful robust multivariate regressions is the minimum covariance determinant, which was proposed by Rousseeuw et al. (2004).
To find the determinant which is the denominator polynomial in (15), we gather the elements of any row or any column of the adjoint matrix after adding to them their corresponding original powers (shifts) which appear in the middle term in (16).
Virulence assays together with a series of experiments enabled us to identify a novel genetic determinant which is required for the overall virulence of Chinese isolates of highly pathogenic SS2.
Death-associated protein kinase (DAPK) is a pro-apoptotic determinant which is dysregulated in a wide variety of cancers [ 65].
The capacity of critical institutions to fulfill their role has been identified as an important system determinant, which is not properly shown in the current TOC.
One (aa 131) of five amino acid substitutions in the S gene was located within the major antigenic determinant, which is the target of neutralizing anti-HBs antibodies.
However, for seeing a psychiatrist, lower age was a determinant, which is in line with previous research showing that mental disorders among the oldest-old are a neglected problem.
Alterations of amino acid G101 and A102 in the porin PorB1b (the penB resistance determinant), which is encoded by the porB1b gene, result in decreased permeability and further decreased susceptibility to ESCs [ 6, 9, 16, 28, 32, 34, 36, 37].
Furthermore, mutations in the promoter or coding sequence of the repressor gene mtrR cause over-expression of the MtrCDE efflux pump system that export the ESCs out from the cell, and alterations of amino acid G101 and A102 in the porin PorB1b (the penB resistance determinant), which is encoded by the porB1b gene, result in decreased influx of the ESCs.
This assumption is justified if the phenotypes are determined by few viral protein functional determinants which are both independent and differ only few DNA bases, i.e. few mutations can change one determinant into another.
