In the USA, a key determinant triggering the need for an NDIN to FDA is whether an NDI which has been present in the food supply has been chemically altered (Federal Food, Drug and Cosmetic Act 1938b).
In spite of the massive lymphadenopathy and documented defects in activated T-cell apoptosis in Bim-deficient lpr mice, it remains uncertain which cell type is the most critical determinant triggering exacerbated autoimmunity in these mice.
However, while application of the purified determinants triggers ISR in the host plant, rhizobacterial knockout mutants that no longer produce the respective determinants were not impaired in their ISR-inducing ability [ 44, 48].
More specifically, in patients who display "effective hypovolemia", either caused by systemic arterial vasodilation or a decrease in cardiac output, arterial underfilling represents the unifying determinant which triggers this cascade of neurohormonal responses.
Hence, future studies utilizing qualitative method or mixed-method are expected to provide a holistic research methodology and a more comprehensive outlook of the antecedents and determinants that trigger entrepreneurial behavior among business students.
By contrast, only a low percentage of Dox-treated control 293Tet cells harboring rKSHV.219 genome exhibited red fluorescence (Figure 3A, 293Tet_rKSHV_C1), suggesting that EBV Rta was the determinant that triggered rKSHV.219 lytic cycle replication.
This strongly suggests that bile aspiration into the lungs may be a major host determinant that triggers the establishment of dominant chronic biofilm-forming microbial species.
In an animal model of CFA-induced paw inflammation, we brought evidence that Bv8/PROK2, upregulated in granulocyte invading the inflamed tissue is a major determinant in triggering and maintaining inflammatory pain [ 3].
Functional characterizations of these individual genes have provided valuable insight into the genetic control of MS formation, yet there remain major gaps in our understanding of the molecular determinants that trigger and regulate MS formation in V. dahliae.
Interestingly, knockout mutants of WCS358 that no longer produced one of these determinants also triggered ISR, which was concluded to be a logical consequence of the redundancy of these determinants.
