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It has recently been conclusively demonstrated that this insert is the sole determinant responsible for the reverse movement exhibited by myosin VI [106,107].
5, 6 The molecular determinant responsible for penicillin resistance was shown to be a plasmid-encoded β-lactamase gene capable of cleaving the β-lactam ring of penicillin.
Possible explanations underlying the co-selection process between metals and antibiotics include co-resistance (different resistance determinants present on the same genetic element) and cross-resistance (the same genetic determinant responsible for resistance to antibiotics and metals) [ 37].
Thus, estrogen deficiency, which occurs after menopause, leads to bone loss through increased osteoclastic function, and represents the major pathological determinant responsible for postmenopausal bone loss, as ROS stimulate osteoclasts that are responsible for bone resorption [ 7, 8].
In addition, the present study demonstrates that LT is not necessarily the only determinant responsible for the increased accumulation of VRN1 in facultative accessions, since this transcript accumulates at late developmental stages in accession Bd21 grown under control conditions (Fig. 3F).
Serotypes were found in similar frequencies among isolates obtained from colonization as well as infections (p = 0.1392), suggesting that the capsule, despite being an essential factor for the virulence in GBS is not the only bacterial determinant responsible for the pathogenicity.
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In contrast, the advances in genome-wide profiling technologies open the possibility of genome-wide scans for genetic determinants responsible for drug response.
Regardless, further work is still needed to characterize the protective response(s) elicited by vaccination with attenuated mutants of type A or type B F. tularensis, and define the antigenic determinants responsible for stimulating this response.
Abiotic stresses, such as water deficit and soil salinity, result in changes in physiology, nutrient use, and vegetative growth in vines, and ultimately, yield and flavor in berries of wine grape, Vitis vinifera L. Large-scale expressed sequence tags (ESTs) were generated, curated, and analyzed to identify major genetic determinants responsible for stress-adaptive responses.
To determine the underlying genetic determinants responsible for SS3's enhanced xylose utilization and ethanol productivity, we used next-generation sequencing (NGS) technologies to identify the potential genetic changes in SS3 as well as SS17 and SS18.
Our data indicated that, while the growth rates of NY99 and chimeric viruses in tissue culture are determined primarily by properties of the structural proteins, determinants responsible for a highly cytopathic phenotype of NY99 or lack thereof for W956 are located within the nonstructural protein region of the WN genome.
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