Sentence examples for determinant of recombination from inspiring English sources

The results indicate that germline methylation patterns are the main determinant of recombination rates in the absence of PRDM9.

A result further supported by the studies conducted on the fast-evolving DNA-binding domain of PRDM9, identified as a major hotspot determinant of recombination.

The human protein PRDM9 has recently been identified as a major determinant of recombination hot spots in human (Baudat et al. 2010; Berg et al. 2010; Myers et al. 2010; Parvanov et al. 2010).

This raises the interesting possibility of DNA sequence and/or other cis- elements as determinants of recombination.

Based on these findings, we propose G4 DNA could be one of the determinants of recombination wherein the single-stranded fold back structure could assist in strand separation and homologous pairing.

The approach can achieve very fine scale resolution, unmasking genomic features and leading to the discovery of determinants of recombination rate variation.

In conclusion, the creation of recombination maps will continue to illuminate new perspectives on the evolution of recombination, shedding light on novel determinants of recombination, patterns of selection, and genome evolution.

Of course one of the most recent, well-studied determinants of recombination, Prdm9, is absent in Drosophila, just one of many other differences that set Drosophila recombination apart from other organisms.

These results provide insight into the molecular determinants of recombination rate variation across the D. melanogaster genome and a clear path for future studies to assess the molecular causes of recombination variation among individuals and its plastic nature.

Our results provide evidence in a multicellular organism that transcription during the initial phases of meiosis increases the likelihood of DSB and give insight into the molecular determinants of recombination rate variation across the D. melanogaster genome.

Nevertheless, our results were quite consistent among maps, indicating that GC content may be the most important determinant of local recombination rates in the honey bee genome at the investigated scale.