Sentence examples for determinant of gene from inspiring English sources

The affinity of transcription factors (TFs) for their target DNA is a critical determinant of gene expression.

As the metabolite-dependent cotranscriptional folding and unfolding dynamics of riboswitches are the key determinant of gene expression, it is important to investigate both the thermodynamics and kinetics of riboswitches both in the presence and absence of metabolite.

However, the linear arrangement of cis-acting regulatory elements is in some context a critical determinant of gene expression.

In D. melanogaster HP1 is known to be a key determinant of gene silencing in the vicinity of heterochromatin blocks [34] and the protein is thought to play a similar role in mammalian cells.

This finding suggests that the promoter is not the critical determinant of gene body methylation status.

Results from all of them support the notion that diversifiability is an important determinant of gene duplicability in evolution.

The efficiency of targeting into both HACs was ∼2 × 10−4, indicating that the number of loxP cassettes in the HAC was not a critical determinant of gene-targeting efficiency.

8) The authors state: "These analyses indicate that not only the Kd but also maximal transcription rate is a key determinant of gene-specific morphogen response... .......... From Figure 7C and 7D, the Kd appears to have no effect on either expression rate or expression range.

Here, we review and attempt to integrate these local determinants of gene expression.

32 (2004) 936 948; A.C. Hsieh, R. Bo, J. Manola, F. Vazquez, O. Bare, A. Khvorova, S. Scaringe, W.R. Sellers, A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens, Nucleic Acids Res.

Only then large-scale mapping of the determinants of gene expression will become truly informative.