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These continuous representations model the flexibility and dynamics of biological macromolecules, which are an important structural determinant of function.
Cardiac histo-anatomical organization is a major determinant of function.
Shape is an important determinant of function, which is precisely reflected by mitochondrial dynamics.
For multidomain proteins we have tended to use the alignment of the ATPase domain as the determinant of function.
Subclinical disease, especially cardiovascular disease, can be a strong determinant of function [ 31] as well as survival [ 32].
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Singh et al. also obtained the bound for the second Hankel determinant of functions in G α.
In the recent years, several authors have investigated bounds for the Hankel determinant of functions belonging to various subclasses of univalent and multivalent functions [20 27].
Although the subcellular locailization of SIRT1 is not a sole determinant of functions of this deacetylase in tumorigenesis, it is evident that the nuclear and cytoplasmic SIRT1 might exert distinct functions.
[4], who determined that fear of movement/reinjury are determinants of function after ACLR.
Although patients with advanced disease have well-documented and profound functional limitations, less is known about the determinants of function in early to mid-stage disease where interventions may be more likely to benefit and preserve function.
Organic chemistry has systematically probed the chemical determinants of function in nucleic acids by variation to the nucleobase, sugar ring and backbone moieties to build synthetic genetic polymers.
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