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Thus, the properties just described for the ADP-bound trailing head are likely critical in preventing back-stepping, which is a key determinant of efficient and rapid motility.
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More studies are required to identify determinants of efficient replication of animal influenza viruses in mammals.
These results provided first evidence that determinants of efficient mobilization are localized in the VNTR domain of LAVA elements.
Thus, inherited differences in the efficacy of the MDM2-mediated limitation of p53-response in stressed cells could be important determinants of efficient tumor suppression [ 8].
These results suggest that the concerted action of several enzymes could be determinant of the efficient hydrolysis of CSCB, rather than only one enzyme specificity.
Both the colony formation rate (number of colonies) and the ratio of correct clones (cloning efficiency) in transformation are important determinants for efficient cloning of PCR fragments.
In this regard, Shavinskaya et al. demonstrated that the lipid droplet-binding domain of the Core is a major determinant for efficient virus assembly [6].
Furthermore, our data show a correlation between cell surface sialic acid availability and the efficiency of infection, suggesting that receptor availability may be a major determinant for efficient infection in respiratory epithelium.
The structural determinants for efficient uptake of extracellular ubiquitin via CXCR4 have been reported recently.
The design of artificial microRNAs [ 54, 55] and its application to both basic and applied research may also greatly benefit from a more detailed identification of the determinants for efficient miRNA biogenesis.
A list of dimensions and determinants for efficient diffusion and adoption are selected through a literature review and a structured hierarchical framework was developed with the help of expert consultation.
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