Moreover, the levels of B-MYB regulated through p53 and pRB determines the fine balance between proliferation, quiescence, and senescence, making B-MYB a determinant of cell fate.
The results revealed that substrate stiffness was the major determinant of cell performance.
The dynamic organization of the cell nucleus into subcompartments with distinct biological activities represents an important determinant of cell function.
Recent advances have revealed that modification of chromatin structure is an important determinant of cell fate and function.
This result points to the important role of porosity of fibrous scaffolds as a major determinant of cell behaviour (Hutmacher 2000).
It is of central importance to metabolic engineering as it is a fundamental determinant of cell physiology and the most important parameter of the metabolic pathway.
The cortex is the main determinant of cell shape and plays a fundamental role in cell division [1 3], migration [4], and tissue morphogenesis [5].
Intracellular Ca2+ plays a major role in the physiological responses of excitable cells, and excessive accumulation of internal Ca2+ is a key determinant of cell injury and death.
Cell interactions with the original matrix became less important as time progressed, while the de novo-produced extracellular matrix became a more critical determinant of cell fate.
Efficient DNA double-strand break (DSB) repair is a critical determinant of cell survival in response to DNA damaging agents, and it plays a key role in the maintenance of genomic integrity.
In recent years, it has become evident that phosphorylation of the alpha subunit of the translation initiation factor eIF2 at serine 51 (eis2αS51P) is an important determinant of cell fate in response to stress.
