Sentence examples for determinant of age from inspiring English sources

The CAG allele size is the major determinant of age at onset (AO) of motor symptoms, although the remaining variance in AO is highly heritable.

46 Thirdly, the positive association between vitamin D concentrations and longer leucocyte telomere length, a potential determinant of age related disorders and overall longevity, 48 emphasises the possible beneficial effects of vitamin D on healthy ageing and associated outcomes.

All brain regions have similar DNAm ages in subjects younger than 80, but brain region becomes an increasingly significant determinant of age acceleration in older subjects (as can be seen from the Kruskal Wallis test p-values in Figure 2i-l).

"To pick out one particular phenomenon of telomere length as a key determinant of ageing and say that if you're going to lengthen telomeres you're magically going to cure ageing, I think that's fanciful".

This observation has pointed to short telomere length as the relevant lesion in the setting of mutant telomerase genes, and more commonly, because telomere length is polymorphic, as an important genetic determinant of age-related disease [17].

Osteoblast dysfunction is the main determinant of age-related decline in bone formation and bone loss (Kassem and Marie 2011).

In addition to examining diet as a modifiable determinant of age-related diseases, there is a need to consider aging as a process consisting of multiple health components.

One way to help understand the molecular changes underlying aging is through a comprehensive analysis of the transcriptome, the primary determinant of age-related phenotypic diversity.

c) How is inflammation and important determinant of aging?

To this respect, diet has been considered to be a determinant of ageing process.

The free radical theory of aging postulates that the production of mitochondrial reactive oxygen species is the major determinant of aging and lifespan.