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In fact, studies with genetically engineered mice have revealed that the activity of lipoprotein lipase (LPL) is a major determinant for the development of obesity.
In working populations, AHR is an important determinant for the development of symptoms[ 3].
Thus, although neutrophil recruitment prevents the systemic spread of the infection, it might nevertheless be a key determinant for the development of gastroenteritis.
Recently, Ohno et al. showed that PPAR-γ ligands, coupled with PRDM16 (a determinant for the development of BAT), could switch subcutaneous white adipose cells to a BAT programme (Ohno et al., 2012).
The relationship between feeds frequency and GOR episodes in both term and preterm infants was investigated at first by Omari et al. [ 2], who observed a positive correlation between the frequency of feedings and the occurrence of nonacid GOR episodes, with a concomitant decrease in the number of acid GOR, which is known to be determinant for the development of GORD [ 31].
These discrepancies could be due to a fat depot-specific effect, as visceral adipose tissue is an independent determinant for the development of obesity-associated metabolic complications (Heilbronn et al, 2004; Ravussin & Smith, 2002), or due to differences in the degree of insulin resistance and further studies are needed to address this point.
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Inflammation and blood flow alterations are new markers emerging as possible determinants for the development of atherosclerotic lesions.
Multivariate logistic regression analysis identified the presence of preoperative atrial fibrillation and preoperative ejection fraction as independent determinants for the development of severe isolated TR.
The purpose of this study is to examine the fetal and early childhood family-based determinants for the development of adiposity, CVD risk factors, and atherosclerosis in childhood.
The incidence of ESRD is 50% higher in males, which makes gender one of the most significant risk determinants for the development of kidney disease.
Volunteers also participated in a study of metabolic determinants for the development of type 2 diabetes and obesity.
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