Sentence examples for determinant for selection from inspiring English sources

The ligand conformation, binding mode studies and drug like properties were major determinant for selection of molecules for final synthesis.

Not surprisingly, functional impairment was the criterion most determinant for selection in the group with severe disease at inclusion, whereas radiological damage became the major reason for selection during follow-up.

Compared with conditions in the wild, host densities in farming conditions are not only high (even extreme under intensive poultry production), but consistently so, which may be a major determinant for selection of high virulence.

Misclassification of KRAS mutation status has important clinical consequences because KRAS testing of tumor tissue is often used as the sole determinant for selection of anti-EGFR therapy [ 19, 20].

These changes meant that English, rather than education in an occupation in demand, was made the key determinant for GSM selection.

In particular, even if the risk factor for HIV acquisition might be a determinant for CRT selection at time of transmission [ 38], it seems to lose its importance over time.

However, a retrospective review of 60 phase I trials of targeted agents reported mainly between 1999 and 2002 revealed that the majority of studies had used toxicity as the sole determinant for dose selection in phase II studies.

Inside the host plant, A. tumefaciens exhibits the T6SS- and Tde-dependent competitive advantage over P. aeruginosa, which suggests that the plant environment is a crucial determinant for the selection of the fittest A. tumefaciens strains.

In these examples, a terminal α1,2-linked mannose residue on the b- or c-branch of Man9GlcNAc2-PP-Dol is a positive determinant for substrate selection by the T. cruzi OST, whereas E. histolytica and T. vaginalis OSTs select donors with a non-glucosylated a-branch in the LLO but do not discriminate between Man5GlcNAc2-PP-Dol and Man9GlcNAc2-PP-Dol (Kelleher et al. 2007).

We wanted to ascertain whether disease-mediated selection is a determinant for survival over different life stages of salmon, and if so, whether the same alleles associated with survival in parr are also important at later stages of the salmon's development in fresh water.

We have found an enrichment of different categories of SNPs in the different structural regions of the kinase domain, suggesting structure-based determinants responsible for selection of tumorigenic mutational hotspots.