As a result, RRT is only offered when there is clear evidence of functional deterioration to a point at which the kidney is unlikely to recover quickly enough to avoid the deleterious consequences of altered renal function.
Epithelial-mesenchymal transition (EMT) is one of the critical processes involved in renal tubulointerstitial fibrosis, which is a common pathway in various kidney diseases, leading to functional deterioration and eventual loss of renal function, regardless of initial cause [ 1, 2].
Furthermore, it can induce cell death and senescence, leading to functional deterioration, associated with aging.
Left ventricular hypertrophy is an adaptive response of the heart to chronic mechanical overload and can lead to functional deterioration and heart failure.
Other variables did show significance *p < 0.05 (logistic regression) The postural alterations that frequently occur with advancing age have led health care professionals to seek new forms for evaluating and identifying factors that contribute to functional deterioration.
It may also explain why the Whitehall cohort is resilient to functional deterioration (several of the mean test scores are higher than published results at similar ages despite more prevalent structural brain changes).
A structured diagnosis scheme enables architects and engineers to simultaneously handle the entire complex process of office building refurbishment or retrofit with respect to deterioration, functional obsolescence of building services, energy consumption and indoor environmental quality.
Disturbances in proper mass transport in IOL materials can lead to deterioration of functional properties for such medical devices, thus studies on the field of mutual interactions between the implant materials and environment components have to be performed.
The caregiving burden of caregivers of PWD was largely related to the constant caring, due to the deterioration of functional capacity of PWD; 32 caregivers needed to invest a great deal of time and effort in the caregiving task.
Not only did the SIMILAR-8 fail to detect deterioration in functional status, but also the point estimate of change was in the direction of improvement rather than deterioration.
