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Acetaminophen was also avoided in this case because of the fear of further deterioration of hepatic function caused by hepatotoxicity by acetaminophen.
Those three patients with prolonged ICU LOS despite absence of hepatic dysfunction yielded either borderline dysfunction with decelerated recovery or prolonged deterioration of hepatic function until day 5.
We initially investigated the deterioration of hepatic function induced by TBI to determine whether injection of hMSCs could decrease the damages.
Thus, chemotherapy-induced HBV reactivation in diffuse large B-cell lymphoma patients who are HBsAg-positive has been considered a serious complication, which is associated with long-term deterioration of hepatic function [ 9].
The onset of the MPV17-associated disease is typically heralded by severe hypoglycemic crises in early infancy, associated with rapidly progressive deterioration of hepatic function, leading to liver cirrhosis and failure.
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Fulminant hepatic failure is clinically characterised by acute severe impairment of hepatic function, causing hepatic encephalopathy within 8 weeks of jaundice [29].
DSePA inhibited radiation-induced hepatic lipid peroxidation, protein carbonylation, loss of hepatic function, and damage to the hepatic architecture.
ICG clearance is frequently used as global marker of hepatic function as it illustrates hepatic purification and also hepatic blood flow [11].
The upregulation of hepatic functions by the 3D coculture was confirmed by analyzing liver-specific functions.
Patients had no deterioration in hepatic function, and no clinically significant deterioration in renal function was observed during the trial, even in patients who entered the trial with mild or moderate renal impairment.
Although TACE is only a transarterial procedure, for which therapeutic efficacy has been proved in randomised prospective controlled studies, the deterioration of hepatic reserve is estimated at 20%58%%, mainly because of ischaemic damage to the nontumourous background liver [ 10, 11], inferring a higher risk of unfavourable reduction in hepatic reserve function in cases with poor hepatic reserve.
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