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No biopsies were available for these patients because they presented no deterioration of graft function (certain cDNA samples were prepared by TcLand Expression S.A., Nantes, France).
Furthermore, elevated plasma ADMA is associated with increased morbidity, mortality, and the deterioration of graft function in RT recipients [ 5].
Taken together, all our findings including histology, laboratory and clinical data confirmed the diagnosis of oxalate nephropathy in both patients with subsequent deterioration of graft function.
A chronic type of host-antigraft response may result in late deterioration of graft function characterized by inflammation and interstitial fibrosis [ 5].
We report two patients with chronic deterioration of graft function after combined kidney and pancreas allograft transplantation who presented with a rare, but not far-fetched cause of kidney failure.
In addition, large lymphoceles may manifest by oedema in the inguinal regions, deterioration of graft function, abdominal discomfort, urgency, vesical tenesmus, compressive syndrome of the vena cava or the portal vein and/or fever.
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Hyperglycaemia was not associated with any delay of graft function.
There was a rate of delayed graft function of 92%.
These benefits were accomplished without metabolic deterioration, independent of diabetes duration or presence of autonomic neuropathy, and persisted beyond the duration of islet graft function.
Graft loss was defined as retransplantation or death, regardless of perceived graft function at the time of death.
Fig. 3 Postoperative course of liver graft function.
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