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The presence of retinal arteriolar abnormalities was not associated with deteriorating renal function.
Still, deteriorating renal function remains an independent factor predicting treatment failure and increased mortality.
Acute renal dysfunction and deteriorating renal function have both been consistently associated with poor outcome in this specific subset of patients [24, 25].
Although haematomas and IRVI may heal spontaneously with conservative management, selective TAE (Figs. 7, 8, 9) is recommended as the established minimally invasive treatment of choice for life-threatening occurrences with persisting or massive bleeding, severe haematuria from communication to the pelvicalyceal system, or progressively deteriorating renal function.
Nonetheless, many experts continue to advocate for PTRA in specific cases of RAS, such as resistant hypertension, haemodynamically significant atherosclerotic RAS (Fig. 1b), FMD-associated RAS (Fig. 2b), deteriorating renal function, bilateral atherosclerotic RAS, tight atherosclerotic RAS in a single kidney, unexplained CHF, and recurrent episodes of flash pulmonary oedema [4, 10].
Deteriorating renal function led to intermittent hemodialysis.
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Diuretics tend to further deteriorate renal function.
This proof-of-concept experiment included a low-dose furosemide-treated group because loop diuretics are often applied in cirrhotic patients and tend to deteriorate renal function.
Those patients were discharged from hospital with more deteriorated renal function.
Umerani and Goyal [ 22] demonstrated an increase in serum creatinine as an indicator of deteriorated renal function in diabetic rats.
By exclusion, pancytopenia was ascribed to proguanil toxicity, likely because of deteriorated renal function by dehydration due to gastroenteritis.
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