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The deteriorated binding could no longer fulfill the function of protecting the body of the book, presenting a strong deformation, a broken sewing, intense ware on the spine and pasteboards, gilding loss, gaps and insect holes, among other damages and signs of degradation (Fig. 1).
Note however that the Enzo-protocol introduces a significantly higher fraction of biotinylated nucleotides with potentially deteriorated binding affinities which provides a tentative explanation of the observed trends.
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This structural plasticity of the BMP type I receptor epitope, which allows BMPR-IA to adapt to different binding partners without deteriorating binding affinities to either one of the partners is possibly a key mechanism by which proteins can achieve binding to more than one interaction partner utilizing the same binding site.
Just hours earlier, the solicitor general, Justin Gleeson, announced he would resign over his "irretrievably broken" relationship with the attorney general, which deteriorated after Brandis made a binding legal direction that all government requests for Gleeson's advice would have to be approved by Brandis's office.
The C-terminal domain in T0510 is a treble-clef finger that lost its Zn-binding site, has deteriorated beyond recognition and has gained the C-terminal β/α-unit.
To determine if the binding affinity of the aptamer was deteriorated in the context of ASAP, the initial rates of fluorescence enhancement were calculated and plotted against the ATP concentrations (Figure 5).
Public transit deteriorated.
Then workers' position deteriorated.
Her health deteriorated.
After 1294, matters deteriorated.
But things quickly deteriorated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com