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Changepoint detection sensitively recognized such portions as distinct domains to provide intuitively more natural boundaries (Additional file 5).
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Based on fluorescence signal recovery measurement, the target BoNT-LcA was detected sensitively and selectively with the linear detection range from 1 fg/mL to 1 pg/mL.
The electrochemical investigations confirm that the small-sized AuNPs on the RGO film can remarkably boost the electrocatalytic activity for the oxidation of Sudan I, which can be used as an enhanced electrochemical sensing platform for the sensitively detection of the toxicant Sudan I.
Our fortilin ELISA system both sensitively (detection limit = 0.4 ng/mL) and reliably (%CV = 8.6%) detected both human and mouse serum fortilins (Fig. 1).
It is essential to detect H2PO4− sensitively.
The ratiometric sensor can sensitively detect H2S with a detection limit of 150 nM by fluorescent spectrum method and 3 μM by naked eyes.
The AuAg-GR based sensor could sensitively detected neurotransmitter serotonin (5-HT) with wide linear detection range (2.7 nM to 4.82 μM), very low detection limit (1.6 nM), negligible interference, and excellent reproducibility.
Human IgE, captured by immobilized goat anti-human IgE on SPR gold film, is sensitively detected by SPR spectroscopy with a lowest detection limit of 1 ng/ml after anti-human IgE aptamer Au NPs conjugates is used as amplification reagent.
Finally, a simulation example is given to show that the designed robust fault detection filter can detect the faults sensitively, and also respond robustly to unknown disturbances.
Hence, P-Fe can selectively and sensitively detect H2PO4− ion by means of "turn-on" detection.
C. botulinum cells or spores can be sensitively detected using polymerase chain reaction (PCR), but the detection of BoNT proteins is considerably less sensitive because of the lack of similar molecular amplification tools.
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