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Previous studies have suggested that fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) might improve the sensitivity of detection recurrence of BC compared to CITs [ 9, 10].
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Lu [ 16] distinguished between early (mammographically detected) and late detection of recurrences in his meta-analysis and also compared mammographically detected recurrence to physical examination.
We could not draw firm conclusions relating to detection of recurrence but compared recurrences between groups.
Comparison of studies relating to the detection of recurrence can be difficult because of differences in the definitions of local recurrence [ 17].
(ii) Detection of recurrence, where the key is whether the presence of detectable CTCs provides a significant time advantage over other approaches to clinical diagnosis.
The outlook for patients with recurrent disease is poor with a mean survival of 1 year after detection of recurrence.
Early detection of recurrence after GKR was important for deciding the treatment strategy in patients with metastatic brain tumor.
CA125 is currently the only biomarker recommended for monitoring of therapy as well as detection of recurrence.
In both cancers, imaging is used for diagnosing nodal metastases, detection of recurrence, and dealing with complications of both the disease and treatment.
The recently introduced 68Ga-PSMA outperforms other PET tracers for detection of recurrence and is therefore expected also to impact radiation planning.
However, when the priority is the detection of recurrence or residual tumors, contrast-enhanced MRI of the breast is useful for characterising parenchymal lesions [11, 13].
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