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Therefore, their studies demonstrate that investigation of intercellular heterogeneity in previously undetectable genome DNA modifications (such as mA and mC) is facilitated by the direct detection of modifications in single molecules by PacBio sequencing.
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There have been considerable advances in the creation of chemical and enzymatic methods that enable the detection of modifications of cytosine bases in genomic DNA.
This condition is considered here as a contextual recognition task since subjects were actively engaged in the detection of potential modifications in the learned environment.
EventMine slightly underperformed other systems in the detection of modifications.
We resequenced and annotated eight B. anthracis genomes in order to test the accuracy of 454 WGS technology for rapid detection of genetic modifications in this organism.
We have developed HMCan, a tool for detection of histone modifications in cancer samples using ChIP-seq data.
The most widely used methods for detection of genetic modifications in plants rely on real-time PCR.
A key challenge in the epigenetics field has been achieving high-resolution genome-wide detection of these modifications in sufficient sample sizes to make claims about disease association.
This new information allowed the detection of modifications caused by QPX at the transcriptional level.
Modification detection in the ID task was also affected by DA, since the frequency of modifications in the GE11 corpus is three times larger than those found in the ID corpus.
Detection of modification sites is based on mismatches between cDNA reads and the consensus.
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