Sentence examples for detection of imbalances from inspiring English sources

Usually, the detection of imbalances is based on spectral analysis and order analysis methods [2].

A computerized system allows analysis of the ratios between both fluorochromes for each chromosome and detection of imbalances.

CytoChip ISCA arrays report the gene content of over 500 recognized disease regions, while they have genome-wide coverage, including subtelomeres and pericentromeres, and support the detection of imbalances as small as 60 Kb.

It is also reassuring for future large scale detection of imbalanced allelic expression that the accuracy of our methods seemed to be similar for cDNA and genomic DNA.

The enrichment of genes to these specific cellular elements is not surprising given that they are highly expressed cellular components and, as stated above, detection of imbalance is greatly aided by high coverage or expression.

Two-Temperature LATE-PCR is also suitable for detection of imbalance allele ratios on the order of 1.5 1 that are generated by loss of heterozygosity (deletion) events involving tumor suppressor genes in human pre-malignant cells in the presence of a two-fold excess contaminating normal cells (Sanchez et al., unpublished data).

In conclusion, array CGH is a powerful method for the genome-wide detection of chromosomal imbalances and allowed us to detect molecular genetic aberrations associated with specific breast cancer subgroups (ductal vs lobular, ER-negative vs ER-positive tumours).

The detection of genetic imbalances at fragile sites may therefore be of value to detect the "signature" of replication stress [ 63] and may assist to characterize pre-malignant lesions.

This recent significant increase in array resolution has allowed the detection of genetic imbalances as small as just a few kilobases in size and also enables the boundaries of an imbalance to be better defined.

In fact, several international organisations have developed various frameworks for the evaluation and early detection of macroeconomic imbalances (European Union or G-20).

Use of milk urea (MU) concentration as a parameter for detection of nutritional imbalances requires identification and quantification of nutritional and nonnutritional factors that influence it.