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Early detection of Heart Failure (HF) could mitigate the enormous individual and societal burden from this disease.
Early detection of heart failure has become increasingly important, as modern drug treatment has the potential to improve symptoms and quality of life, slow down the rate of disease progression, and improve survival.
Furthermore, novel nuclear imaging techniques are being developed that may provide more detailed information for the detection of heart failure in an early phase as well as for monitoring the effects of new therapeutic interventions in patients with heart failure.
These molecular-targeted imaging techniques will provide further insight into the pathophysiology of the failing heart and may potentially be used for early detection of heart failure as well as monitoring new therapeutic interventions.
Notably, individual serum NTproBNP levels exceeded the suggested decision cut-point for the detection of heart failure (125 pg/ml; Cowie et al. 2003) at some time points during the race in all runners and remained abnormally high in most of them at the end of the run, but normalized 48 h post-race.
In patients with the suspicion of heart failure several other studies showed natriuretic peptides to be useful indicators for the detection of heart failure (Lerman et al, 1993; Davidson et al, 1996; Cowie et al, 1997; Hammerer-Lercher et al, 2001; Maisel et al, 2002, 2003).
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Detection and treatment of heart failure (HF) can improve quality of life and reduce premature mortality.
Unfortunately, currently used diagnostic methods are insufficient for early detection of the risk of heart failure or arrhythmia, which would enable life-saving treatment.
A new PET radiotracer could enable early detection of the risks of heart failure and cardiac arrhythmia, and thus save more lives.
The best was judged to relate to the detection and evaluation of valvular heart disease, the diagnosis and treatment of heart failure, the jugular venous pulse in the assessment of central venous pressure, and the detection of atrial fibrillation, peripheral arterial disease, impaired perfusion, and aortic and carotid disease.
With the tissue Doppler imaging technique, measurement of myocardial tissue velocity allows detection of early diastolic wall motion abnormalities before development of heart failure.
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