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Nevertheless, detection of a recurrence should lead to curative therapy with an aggressive surgical approach.
In the clinical setting in which patients have suspected recurrence, it is unclear which whole-body staging modality is most accurate for the detection of a recurrence.
Another group in Europe reported surveillance costs of US$9,011 [ 10] to US$59,841 [ 11] per detection of a recurrence resulting in attempted curative salvage surgery.
Patients reported a strong preference for follow-up, and a large majority would prefer follow-up even if it would not lead to earlier detection of a recurrence.
For advanced stage mucinous LMPs, earlier detection of a recurrence may not always result in improved prognosis, due to the lack of efficacious chemotherapy (Tamakoshi et al, 1997).
Kaplan Meier curves for the time from baseline until the detection of a recurrence of the disease during follow-up were obtained, and ITT analysis performed.
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For some of these markers, particularly the UroVysion FISH test previous studies have shown that a positive marker might precede visual or histologic detection of a tumor recurrence.
Time to loco-regional failure was defined as the period between the start of RT and the detection of a local recurrence.
The main objectives of these visits are the early detection of a locoregional recurrence or a second primary breast cancer, detection and registration of side effects of treatment, and provision of information and psychological support [ 1, 2].
This percentage has grown up to 100% of patients who underwent radiotherapy alone or inadequate surgery with ILM with the detection of a local recurrence within 17-20 months from primary surgery.
Intensive monitoring allowed earlier detection of all recurrences, with an average of 8.5 months (95% confidence interval 7.6 9.4 months), and a higher detection rate of isolated local recurrences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com