There was no detectable loss of ciliary PA-GFP signal or ciliary Alexa555 (Flag) signal after 28 consecutive images.
Previously, investigators have reported detection of Cyp1b1 mRNA in the ciliary body and epithelium and neuroepithelium in the developing mouse eye, employing in situ hybridization techniques.
Axokine is a genetically engineered form of ciliary neurotrophic factor, a protein that promotes survival of nerve cells.
Knockdown of ciliary proteins significantly reduced self-renewal capacity.
These are useful in the simulation of ciliary beats, flagellar motion, and particle suspensions.
Thus, while loss of cilia, loss of ciliary structure, or loss of ciliary signaling without doubts results in cystic kidney, a ciliary pathway might be overactive and contributing to progressive cyst growth during the course of ADPKD.
Congenital disorders of ciliary beating, referred to as primary ciliary dyskinesia (PCD), are characterized by deficient mucociliary clearance and severe, recurrent respiratory infections.
Intraoperatively, atrophy of ciliary processes was noted along with multiple peripheral retinal breaks.
To investigate the correlation among preoperative biometry data, postoperative ciliary sulcus diameter, posterior vault distance, and effective lens position of ciliary sulcus implanted intraocular lenses (IOLs).
Here, we discuss recent advances in the identification and characterization of ciliary signaling components and pathways.
