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Two investigations evaluate Bayesian meta-regression for detecting treatment interactions.
The role of imaging includes tumour staging, treatment planning, assessing treatment response, and detecting treatment complications and recurrent disease.
Assessing cognitive and functional changes at the early stage of Alzheimer's disease (AD) and detecting treatment effects in clinical trials for early AD are challenging.
A single 24-hour recall rating was about as valid (sensitive) for detecting treatment effects as composite scores made up of 2 to 9 different ratings.
IPD-Analyses are used to answer specific questions, e.g. on subgroups, to adjust for confounding factors and to increase the power of detecting treatment effects and sources of heterogeneity [9],[9]],[9]].
Our investigation shows that a Cox regression model applied to the entire cohort is often a more powerful tool in detecting treatment effect as compared with a matched study.
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The purpose of this article is to elucidate the various systemic therapies used in breast cancer, with an emphasis on the role of imaging in assessing treatment response and detecting treatment-related toxicities.
Panel B of Figure 1 also shows how the overall pre-treatment risk of the study population increases, the likelihood of detecting treatment-effect heterogeneity diminishes for both the conventional and multivariable approach.
The International Index of Erectile Function is a reliable, self-administered measure of erectile function that is cross-culturally valid and psychometrically sound, with the sensitivity and specificity for detecting treatment-related changes in patients with erectile dysfunction.
Both the MSHQ and the MSHQ-EjD Short Form have demonstrated sensitivity for detecting treatment-related effects in men with LUTS/BPH enrolled in the BPH Registry and Patient Survey (Rosen et al 2007b).
Although most tinnitus questionnaires were designed to measure tinnitus complaints at the time but not the change of tinnitus over time, they are often used for detecting treatment-related improvements and also serve as a primary endpoint in clinical trials.
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