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Capability of 2 gait measures for detecting response to gait training in stroke survivors: Gait Assessment and Intervention Tool and the Tinetti Gait Scale.
We also outline selection of appropriate proxy outcome measures for detecting response to treatment and collection of ancillary data, such as diet and substance use, that are critical for interpretation of results.
In this context, we investigated the role of 111In-bevacizumab in detecting response to anti-angiogenic therapy targeting mTOR.
The use of MR and US imaging for detecting response to therapies has also been investigated.
DW-MRI also shows promise as an early surrogate biomarker for detecting response to neoadjuvant chemotherapy.
Thus, objective physiological measurements may be more sensitive and accurate in detecting response to treatment than clinical assessments.
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We consequently predict that agonist ligands should likewise be fitter than antagonists for detecting responses to denervation in positron emission tomography studies of idiopathic Parkinson's disease.
We show here, in a model of human breast adenocarcinoma, that a combination of hyperpolarised [1-C]pyruvate and [1,4-C2]fumarate can be used to detect response to doxorubicin treatment before there is any detectable change in tumour size.
Imaging also offers an opportunity to detect response to HER2-targeted therapies in BC [13].
The probability of linking newly detected response to the existing trajectory is defined according to the appearance affinity, position affinity, and size affinity [23].
It seems unlikely that any single marker can offer sufficient sensitivity and specificity to predict the progression of arthritis and detect response to medical treatment.
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