Using yeast as a biosensor improves the sensitivity for detecting expansions compared with most biochemical methods.
The Fu's test, and other statistics relying on haplotype frequencies, were found to be more sensitive for detecting expansions on nonrecombining genomic regions than Tajima's D and other tests [ 52].
However, we detect expansion counties surrounding a compression county and vice versa.
Out of all detected expansion phases, we selected those with AL minima of at least −50 nT.
Moreover, the genome has many contracted gene families, yet we detect expansion of a few families.
Eighty-nine subjects from a previously described panel of individuals with bipolar disorder ascertained for genetic studies were screened to detect expansion of the C9ORF72 repeat.
For example, with the inclusion of expansion within demes as well as global expansion, the power to detect expansion with local samples increases and negative Tajima's D is expected at lower levels of migration (4Nm < 5; Figure 6A).
Since all inferences of demographic histories were based in one or the other way on mutation spectre in observed data, it is not possible, in our opinion, to detect expansion times older than the data themselves, supporting a more recent expansion of benthic species.
These results demonstrate that GFP− and GFP+ cells accurately reflect the presence of expansions and contractions, making this assay especially well suited to detect expansions and contractions quickly within a chromosomal environment.
In the other two species, O. barthii and O. punctata, the detected expansions and contractions were nearly similar in number (Table 1), raising an intriguing possibility that the African species are under some sort of selection regime for genome size, i.e., either recalcitrant for genome expansion, or even some are on the path to genome downsizing.
