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Taken together, our data newly show that LPA responses to mycobacterial antigens are capable of detecting a spectrum of TB disease from latent to active and disseminated disease.
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Given the simplicity in design of the proposed electrochemical aptasensor, it is fairly easy to generalize this strategy to detect a spectrum of targets by splitting the aptamers into two suitable segments.
Like with most DNA-based tests, it must be emphasized that the current assay detects a spectrum of common and highly prevalent ESBL-associated mutations without a precise identification thereof.
We pooled sera from five patients with different disease presentations in order to detect a spectrum of reactive antigens.
It will be important to determine whether this subtask detects a spectrum of capability in patients with more severe shoulder conditions.
For the proposed schemes, we derive the total probability of error of detecting a spectrum hole.
Bloodsucking insects such as mosquitoes are attracted by thermal (heat) radiations of warm-blooded hosts; snakes such as pit vipers can locate warm prey at considerable distance by means of extremely sensitive receptors that are capable of detecting a broad spectrum of thermal radiation, including infrared and ultraviolet.
Karyomapping is potentially capable of detecting a wide spectrum of monogenic and chromosome disorders and, in this context, can be considered a comprehensive approach to PGD.
Our goals for this study were to develop methods for design of gene family-specific probes, to measure the sensitivity and specificity of these arrays, and to assess the validity of the FGA approach for detecting a broad spectrum of virulence and antibiotic resistance mechanisms in unknown as well as known microorganisms without culturing them.
As shown in Figure 2b, this antibody, while detecting a broad spectrum of acetylated residues, preferentially recognizes acetyl-lysines present on histone H4 in comparison to acetyl-lysines found on H2A, H2B, or H3.
The lesions detected were a spectrum of benign, pre-malignant and malignant pathologies.
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