Contraindications to lithium treatment were of course more prominent in the non-Li group; however, we did not detect major differences in the patient groups' comorbidity profiles.
Furthermore, even if our study was not powered to detect major differences in outcomes, the TEG protocol allowed the administration of lower heparin doses without an increase in thrombotic complications and with a tendency for less bleeding compared to the aPTT protocol.
No significant differences were observed, but this trial only had power to detect major differences in survival without oxygen or on ventilator.
In agreement with their in vivo findings, we did not detect major differences in astrogliosis, as evaluated by GFAP expression between control and PSA-NCAM expressing cells.
This decision was made before unblinding, and we did not detect major differences in results when these participants were added back into the analysis.
The number of doctors who took part was sufficient to detect major differences in CARE Measure scores between doctors with a high degree of reliability.
Moreover, when we analyzed the two KTx-patients in the respective eGFR category, i.e., excluding them from the RRT category, we did not detect major differences in the findings, except in the variable describing kidney function.
No significant differences between HFOV and CV were observed, but this trial only had power to detect major differences in mortality or survival without oxygen dependency or on ventilator.
Using Western blotting and Phos-Tag technology, we were unable to detect major differences in yeast Rfa2 phosphorylation in the rfa2 NT mutants, except for an additional phosphospecies in the damage-sensitive rfa2 mutants only.
