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Sentinel groups detected large changes in prevalence of nonsusceptibility over time but rarely detected emerging fluoroquinolone resistance.
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Here, we show that another property of the signaling system is to detect large changes in light while at the same time, filtering types of fluctuation in light that do not affect photosynthesis efficiency.
Another one is de novo sequence alignment to detect large changes in the genome, for example, in cancer patients.
They can only detect large changes in expression and require an extensive downstream validation with complementary low-throughput experiments and large sample size.
Local and global assays of whole-brain glucose utilization with different methods give equivalent results, but global assays cannot detect large changes in small structures.
The pool size of approximately 40 strains was chosen to keep the total number of mice in the experiment low, while enabling us to detect larger changes in mutant abundance.
The large variation in population estimates due to many forms of stochasticity (e.g. seasonal differences in decay rate, sampling bias and inter-nest variation in decay rate) appear to make it difficult to detect even large changes in population size.
It is noteworthy that even though mutant SOD1 was expressed in a subset of neuronal cells, we were able to detect relatively large changes in expression of genes that function within the nervous system.
However, we have detected large numbers of significant changes in the database that occurred during the time period of this study.
We investigate word occurrences, and their changes over time, as reflected in their distribution; we show that using these relationships we are able to detect large-scale changes in the annotation process; and we demonstrate that the parameters of these relationships also change.
A DNA microarray analysis detected large-scale changes of gene expression in response to Cd stress with a substantial difference between the two genotypes.
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