The algorithm successfully detected interactions between multiple competing threads in distinct virtual machines on a multi-core machine.
To this end, we titrated the strength of the detected interactions with 3-aminotriazol (3-AT).
Instead, we detected interactions only when NubG was placed on the carboxyl terminus.
As is shown in Figure 5, the detected interactions regard only few, but interesting, genes with decreased expression in tumour.
Similarly, we detected interactions of IGFBP2 rs4402960 with the same loci (P = 0.02, P = 0.01 and P = 0.008, respectively).
These data are commonly represented as networks, with nodes representing proteins and edges representing the detected interactions (Figure 1).
However, in the Health 2000 Survey women, associations were not adjusted for alcohol consumption, smoking or physical activity due to detected interactions.
Correlations between protein degree, or number of detected interactions, and cellular protein and mRNA abundances were determined with no averaging or binning of data.
Therefore, an investigation into any influences the cellular concentration of each protein has on the detected interactions should be based on protein abundance measurements.
We suggest that the detected interactions are of importance for hematopoiesis and could provide new insights into individual response to treatment.
Since in vivo abundances of many proteins are often less than when tagged in Y2H experiments, the detected interactions may not necessarily occur in the natural environment.
