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Since most medicines are administered orally, we expected that most of the detected counterfeit medicines in the CIS reports would have oral route of administration, which is what we observed.
2 4 This patient safety failure was first uncovered in 2012 when the US Food and Drug Administration FDAannouncedced it had detected counterfeit or fake versions of the injectable anticancer drug Avastin (INN: bevacizumab) in the US controlled drug supply chain.
Specific to CIS, better and normalized data regarding the verified quantity of detected counterfeit medicines and details on the level/location of detected supply chain penetrations may provide more robust information, but have their own challenges in ensuring accurate reporting based on information collected from the field.
Counterfeit Incident reports included 1,799 different counterfeit medicine detections ("Detected Counterfeit Medicines") penetrating the legitimate medicines supply chain for the 36-month period from 2009 to 2011 as reported in CIS.
Therapeutic categories for the Detected Counterfeit Medicines in Counterfeit Incident reports are summarized in Table 2.
This is notable given that noncommunicable disease, branded products are likely the focus of internal member-based CIS database reporting, yet still are found with a lower number of Detected Counterfeit Medicines reports than anti-infectives.
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