Rather, the invariance of transcript abundance among MA lines was consistent with low segregating variation in the inbred ancestral line and with the estimated 34 mutations per MA line being insufficient to generate detectable mutational variance in most genes.
Assuming a range in R of 0.05 -0.30, a power of 0.80 and a 10-parameter model, minimum detectable incremental variance in outcome explained by infant feeding practices (intensive lactation vs. intensive formula feeding) ranges from 0.55% to 0.75%, depending on the explanatory power of confounding variables included in the model (Table 3; calculations presented are for the one-year visit).
Without a noticeable intra-cluster variance the detectable difference will increase by 9%.
As mentioned above, almost all of the detectable significant genetic variance for the morphological traits was found in the 27°C treatment, and we detected only CVA for ovary mass at 23°C.
Changes in synaptic variances were detectable at 3 months, and at 6 months BACHD mice display progressive synaptic pathology in the form of reduced cortical excitation and loss of inhibition onto pyramidal cells.
At absolute curvatures of 0.1, the improvement that could still be made can be too small (less than 3% reduction of variance) to be detectable.
Following standard formulae, for a trial using individual randomisation[ 14], for fixed power (1 - β) and fixed sample size (n) per arm, the detectable difference, d I, with variance var(d I) = 2 σ /n I is: (1) where z α /2 denotes the upper 100 α/2 standard normal centile.
While this sampling density is still larger than the diameter of capillary structures, the presence of microvessels within a given image voxel was still sufficient to cause detectable differences in the intensity variance compared to voxels lacking vasculature.
We used array CVs to test if array age could explain some of the variance and found no detectable effect (R2 = 0.025, F69,1 = 2.73, P = 0.103).
At variance, GFP+ cells were not detectable in the lesion core after pMCAo (Figure 3H) or TBI (Figure 3N).
Within-nest variance in the length of detectable exchange gaps accounted for 80% of the overall phenotypic variance (Table 5).
