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Surprisingly, we did not detect significantly different telomere erosion rates in shStn1-1 knoculturesultures (42 bp/PD, Fig. 3D) compared to control cells, suggesting that only partial knockdown of Stn1 does not affect telomere erosion rates to a degree that is detectable by TRF analysis.
However, we would further like to propose the possibility that the high number of existing amyloid plaques at this age and therefore the large total surface area where newly formed Aβ fibrils can attach to existing plaques could lead to a decelerated growth of each individual plaque up to a degree that it is not detectable by two-photon in vivo imaging anymore.
To a degree.
Well, to a degree.
To a degree, yes.
"To a degree," she said.
To a degree he has.
To a degree, at least.
To a degree, they succeeded.
Fair enough — to a degree.
To a degree, he has a point.
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