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For our analysis, a detectability level of more than 5 dB corresponding to an SNR of −12 dB has been chosen as a detection criterion to be on the safe side.
As a consequence, D2O concentrations above 60% were not studied because the dilution required would render the GFP yields below the detectability level.
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The normal concentration range fell below the detectability levels of this method.
Although the results using a simple detectability hypothesis are encouraging, it seems likely that there are benign pathologies that also produce detectable levels of tCho.
However, this highly sensitive procedure can detect prion concentrations below the level of detectability of bioassays.
α-Synuclein is expressed predominantly in neurons where it is localized to presynaptic terminals [ 70- 72] and is expressed only at very low levels or levels below detectability in oligodendrocytes [ 73, 74], and its expression is not increased in MSA [ 63, 66, 73].
These experiments serve to establish receptor mRNA expression levels and detectability using different probes and detection protocols as described for the probes used in the present experiments and are a necessary prerequisite for choosing appropriate ISH protocols for multiple labeling.
For higher activity accumulation targets, using the 0.5-mm-pinhole collimator (smaller diameter) will provide better spatial resolution with a good level of detectability, i.e. beyond the threshold value based on the Rose criterion of detectability (Figs. 11 and 12).
"It was below the level of detectability, but there can still be some leukemia cells present".
Specifically, numerical simulations were performed to study the correlation between passive neutron emission rate of an irradiated pebble and its burnup level, the detectability of passive neutron emission from an irradiated fuel pebble by commonly used neutron detectors, and these detectors' abilities to discriminate gamma interference.
However, using longer acquisition times helps to provide a detailed image with an acceptable level of detectability (Fig. 10 upper row).
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