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The shortest path (geodesics) was calculated to evaluate the network and parameters, such as degree (connectivity), betweenness centrality (BC) and closeness centrality (CC), were used to detect the essential proteins as putative drug targets.
Due to the use of a less resolutive columnar approach, earlier autoradiographic studies of hypothalamic progenitor domains did not detect the essential distinctness of the paraventricular and subparaventricular alar areas (nor separated these efficiently from the preoptic area; e.g., Altman and Bayer 1986 , 1988.
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He was brilliant at impersonating a ranking headquarters cop to crash a crime scene and detect the essentials first-hand.
Typical orthopoxvirus sequences were revealed in lung tissue samples by use of a novel multiplex PCR assay, which detected the essential DNA polymerase gene; however, the standard single-gene PCR and RFLP analysis did not show the presence of monkeypox virus.
Of course, the ability to reliably detect the feature X is essential.
As a protein with hemagglutinating activity and selectively inhibiting the growth of human tumour cells, it was essential to detect the immunomodulatory activity of RBUP.
Although detection of higher copy number will inevitably be less accurate because of the saturation effects in both hybridization and scanning, it is essential to detect the highly amplified regions in some cancer samples.
Therefore, it is essential to detect the links between ADRs and pathways by a systemic approach.
Although the predominant pathogens are similar, ongoing surveillance is essential to detect the emergence of resistant species.
In addition, according to the recent guidelines for monitoring autophagy, it is also essential to detect the autophagic flux to accurately ascertain the induction of autophagy [ 19].
Identification and characterization of circulating influenza viruses is essential to detect the emergence of antigenic drift variants causing influenza epidemics and novel A subtypes with the potential to cause an influenza pandemic [ 2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com